Many drugs, in fact, are analogues of each other, for some reason have different costs. Because of this, the patient is difficult to determine the purchase, there is confusion and even mistrust of the doctor, who appointed a more expensive medication. Such situations are not uncommon when choosing Capoten or Captopril - which is better to acquire is not entirely clear, because the composition of these funds is almost identical, and their prices are significantly different.
Kapoten or Captopril - is there a difference in effectiveness?
The action of any medication depends on the substance on which it is based.
Captopril is based on the eponymous component, which is an inhibitor of the ACE-angiotensin-converting enzyme. The mechanism of its hypotensive work is to suppress ACE activity, to eliminate the narrowing of the venous and arterial blood vessels. Additionally, captopril produces such effects:
- decrease in afterload (peripheral resistance);
- an increase in the minute volume of the heart;
- decreased blood pressure;
- improving the stability of the heart to the load.
The active ingredient of Kapoten is also one substance and this is also captopril. Both considered antihypertensive drugs are available in the form of tablets with a dosage of the active component of 25 and 50 mg.
The indications for the use of the presented drugs are absolutely identical:
- Renovascular hypertension;
- Diabetic nephropathy on the background of type 1 diabetes mellitus, under the condition of a normal albuminuria level (not less than 30 mg / day);
- violation of left ventricular function due to myocardial infarction, if the patient is in a stable clinical condition;
- classical hypertension;
- cardiomyopathies of various types;
- congestive heart failure (as part of a combined treatment regimen).
Also, Kapoten and Captopril in combination with other medicines can be used as an emergency therapy for hypertensive crises, severe forms of hypertension, provided diuretics are taken.
Apparently, the described drugs can be considered equal in terms of the effect produced.
What is the difference between Capoten and Captopril?
Given the above facts, it turns out that these drugs are completely identical. But at the same time Kapoten is much more expensive and cardiologists often prefer to appoint it. Differences should be sought in the composition of antihypertensive drugs.
The difference between Capoten and Captopril is evident if we study the auxiliary components in the drugs under consideration.
The following are used in Kapoten:
- corn starch;
- lactose (milk sugar);
- microcrystalline cellulose;
- stearic acid.
Captopril has a broader list of additional substances:
- potato starch;
- microcrystalline cellulose;
- talc (magnesium hydrosilicate);
- magnesium stearate.
Thus, Captopril is considered a less "pure" drug, so the cost of its production is smaller, and it costs less. This does not affect the effectiveness of antihypertensive medication, but the presence of talc in the composition sometimes causes negative side effects.
Analogues of Kapoten and Captopril
The described drugs are not the only tablets to reduce pressure on the basis of captopril. Instead of them you can buy the following means:
- The Kaptopres.
Some of them are cheaper than Kapoten, but are not inferior to it in terms of cleaning and minimal maintenance of auxiliary ingredients.